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KMID : 0352519820190020473
Korea Univercity Medical Journal
1982 Volume.19 No. 2 p.473 ~ p.478
A Clinical Study on Postangiographic Proteinuria
ï÷Фܷ/Chung, Kyoo-Byung
õËÙ¥à¾/ßïê¹úÓ/Choi, Myung-Sun/Suh, Won-Hyuck
Abstract
The contrast medium is widely used in modern diagnostic radiology for angiography, urography, cholangiography, CT scan and other many radiological studies. Recently, using iodine contrast media are excellent for the diagnostic aids and relatively harmless to the human organs. But there are a few reports of renal failure following intravascular administration of contrast media, and proteinuria following nephroangiography.
We studied the levels of blood urea nitrogen, serum and urine creatinine, and urine protein prior to the angiography, at one hour, 6 hour and 12 hour after angiographic studies, respectively. The study consisted of 15 patients, 9 males and 6 females, and the mean age was 43, range from 26 to 57 years. All the patients had no evidence of renal problem prior to the study. The angiographic studies were including 6 cases of abdominal aortography with selective celiac arteriography., 4 cases of left ventriculography, 3 cases of cerebral arteriography and 2 cases of femoral arteriography. The contrast media was diatrizoate meglumine 60%, 70o or iothalamate meglumine 60%, and the mean dose was 1.5ml/kg of body weight.
The summerized results were as follow:
1. There was no significant change of blood urea nitrogen or serum creatinine level before and after angiography.
2. The urine protein became two times at one hour after angiography, and 3 times at 6 hour.
3. The urine creatinine was decreased at 6 hour after angiography, but the difference was not significant comparing to the protein elevation.
4. The urine protein, creatinine and protein/creatinine ratio were normalized at 12 hour after angiography.
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